382 Gene polymorphism of 5, 10-methylene tetrahydrofolate reductase is related to boar semen quality

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Prevalence of methylene tetrahydrofolate reductase polymorphism in South Indian population

Prevalence of methylene tetrahydrofolate reductase (MTHFR) gene mutations in South Indian population was investigated from a total of 608 samples, 420 adults and 188 newborns. Detection of mutation was carried out focussing on the two most common mutations of the MTHFR gene (C677T and A1298C) using PCRbased RFLP method. T-allele frequency was almost similar between the newborns and adults (0.09...

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Review Article Methylene Tetrahydrofolate Reductase Gene and Coronary Artery Disease

Hyperhomocysteinemia has been identified as a risk factor for coronary artery disease (CAD).1-9 In a nested case control study in Norway on 21,826 subjects in general population, hyperhomocysteinemia was clearly identified as an independent risk factor for CAD with no threshold level.9 Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the methylation of homocysteine and its role in...

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[Mutations in the methylene-tetrahydrofolate reductase gene and Down syndrome].

Down syndrome (DS) is a complex genetic and metabolic disorder attributed to the presence of three copies of chromosome 21. The extra chromosome derives from the mother in 93% of cases and is due to abnormal chromosome segregation during meiosis (nondisjunction). Except for advanced age at conception, maternal risk factors for meiotic nondisjunction are not well established. A recent preliminar...

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Methylene-tetrahydrofolate reductase contributes to allergic airway disease

RATIONALE Environmental exposures strongly influence the development and progression of asthma. We have previously demonstrated that mice exposed to a diet enriched with methyl donors during vulnerable periods of fetal development can enhance the heritable risk of allergic airway disease through epigenetic changes. There is conflicting evidence on the role of folate (one of the primary methyl d...

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Evaluating Boar Semen Quality

Determining the initial quality of a boar ejaculate is the first step in semen processing and should ensure that prior to further processing, a high quality artificial insemination dose of semen will be produced. Effective screening methods for ejaculates prior to processing are necessary for improving on farm reproductive performances. Ideally, ejaculates that are thoroughly evaluated prior to...

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ژورنال

عنوان ژورنال: Journal of Animal Science

سال: 2019

ISSN: 0021-8812,1525-3163

DOI: 10.1093/jas/skz258.293